Efficient Synthesis of 2,5-Diketopiperazines by Staudinger-Mediated Cyclization
نویسندگان
چکیده
منابع مشابه
A convenient synthesis of difficult medium-sized cyclic peptides by Staudinger mediated ring-closure.
Novel, efficient and mild preparation of 7- and 8-membered cyclic di- and 10-membered cyclic tripeptides containing α-, β- or γ-amino acid residues is effected by a Staudinger-mediated ring closure. Medium-sized cyclic di- and tripeptides--recognized as difficult targets--were obtained in moderate to good yields according to a straightforward sequence. Empirical force-field calculations were un...
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ژورنال
عنوان ژورنال: Synlett
سال: 2012
ISSN: 0936-5214,1437-2096
DOI: 10.1055/s-0031-1290446